Psychological detachment is a work/work-stress recovery strategy that is presumed to reduce stress and improve employee health and happiness. However, psychological detachment could increase stress when it diminishes employees' eudaimonic (i.e., self-actualisation and fulfilment) and/or hedonic (i.e., pleasure) well-being. This research study's objective is to test the mediating effects of eudaimonic and hedonic well-being on the relationship between psychological detachment and work stress. Data were collected through a three-week longitudinal survey in Mexico. The data were analysed using the PROCESS Macro in SPSS\. The results indicate that psychological detachment is positively related to work stress through a negative influence on eudaimonic well-being. The mediating effects of hedonic well-being were non-significant. The findings suggest that psychological detachment is not a one-size-fits-all solution to recover from work stress; alternative recovery strategies need to be tailored to help specific individuals maintain health and happiness.