This article aims to investigate the impact of a business model on bank performance and stability, with a focus on net interest margins. Using a large sample of 300 commercial banks covering 46 African countries, we define the business model by the income structure. Overall, we find that the shift toward non-interest income is associated with a decrease in net interest margins and overall performance. Besides, we observe limited, if any, impact on stability on average. Thus, our results suggest that African banks do not clearly benefit from diversification. However, the results show that ownership and size matter. JEL Codes: G21, G32, N27