Real-time work and data-driven (DD) strategies are gaining popularity in Industry 4.0, which highlights the importance of revising the statistical methods applied in these environments. This study is the first systematic literature review on advanced statistical methods for real-time industrial process analysis (ASMs-RTIPA), offering valuable insights for future research by compiling existing recent studies (from 2014 to 2020) systematically. The review indicates a lack of publications on ASMs-RTIPA, yet it supports its application. Approximately 41% of the selected publications use case studies, 23% develop models, and 18% are conceptual. 'Advanced process control' is the most common keyword in the publications studied. The majority of publications come from the USA, UK, Germany, and the Netherlands. Engineering, generally, has the highest concentration of publications on the subject.