Museum Information Systems (MIS) often rely on manual classification and keyword search, limiting accuracy and scalability. Deep learning offers a solution, but effective integration requires alignment with curatorial workflows. This study proposes a model-driven framework for integrating Convolutional Neural Networks (CNNs) into MIS to enhance artifact classification and retrieval. A prototype was built using ReactJS, Django, and TensorFlow, and it was trained on a curated subset of The Met's Open Access Images. The system employs a Hybrid-E Loss for improved classification accuracy. The model achieved 94.3% classification accuracy and real-time retrieval latency below 100 ms, with throughput exceeding 14 queries per second. The framework successfully bridges AI performance with curatorial logic, demonstrating a scalable and interpretable solution for digital heritage systems.