Patents, Innovation, and Competition in Pharmaceuticals: The Hatch-Waxman Act After 40 Years

C. Scott Hemphill & Bhaven N. Sampat

Journal of Economic Perspectives2025https://doi.org/10.1257/jep.20241423article
AJG 4ABDC A*
Weight
0.53

Abstract

A central policy issue in pharmaceuticals is how to balance the dynamic benefits of new drugs against the static benefits of low prices for existing drugs. In the United States, that balance is set by the Hatch-Waxman Act. We review the Act's origins and key features, then present evidence on its effects on competition and innovation. On the competition side, we show how the Act creates incentives for brands to accumulate patents and generics to challenge them, with the result being a rough stalemate. We also discuss strategies deployed by brands to delay generic entry. On the innovation side, we show that the Act's patent extension provisions — which aim to allow branded firms to make up for time lost during clinical trials and regulatory review — are incomplete, resulting in potential distortions. The net result is a convoluted and expensive approach to balancing innovation and competition.

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https://doi.org/https://doi.org/10.1257/jep.20241423

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@article{c.2025,
  title        = {{Patents, Innovation, and Competition in Pharmaceuticals: The Hatch-Waxman Act After 40 Years}},
  author       = {C. Scott Hemphill & Bhaven N. Sampat},
  journal      = {Journal of Economic Perspectives},
  year         = {2025},
  doi          = {https://doi.org/https://doi.org/10.1257/jep.20241423},
}

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Evidence weight

0.53

Balanced mode · F 0.40 / M 0.15 / V 0.05 / R 0.40

F · citation impact0.50 × 0.4 = 0.20
M · momentum0.70 × 0.15 = 0.10
V · venue signal0.50 × 0.05 = 0.03
R · text relevance †0.50 × 0.4 = 0.20

† Text relevance is estimated at 0.50 on the detail page — for your query’s actual relevance score, open this paper from a search result.