The Italian Assessment System for Innovative Medicines: An 8-Year Retrospective Analysis of Outcomes, Criteria, Timelines and Funding Dynamics

Lorenzo Martellone et al.

Applied Health Economics and Health Policy2026https://doi.org/10.1007/s40258-026-01032-8article
AJG 1ABDC C
Weight
0.50

What the paper says

The Italian system has been applied consistently over time, with appraisal outcomes largely reflecting the formal decision criteria rather than regulatory status. The 2025 reform may represent a turning point, potentially changing designation patterns and their determinants. Ongoing monitoring is needed to ensure access does not compromise evidence standards or sustainability, offering lessons that may be relevant to other health systems considering similar mechanisms.

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https://doi.org/https://doi.org/10.1007/s40258-026-01032-8

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@article{lorenzo2026,
  title        = {{The Italian Assessment System for Innovative Medicines: An 8-Year Retrospective Analysis of Outcomes, Criteria, Timelines and Funding Dynamics}},
  author       = {Lorenzo Martellone et al.},
  journal      = {Applied Health Economics and Health Policy},
  year         = {2026},
  doi          = {https://doi.org/https://doi.org/10.1007/s40258-026-01032-8},
}

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Evidence weight

0.50

Balanced mode · F 0.40 / M 0.15 / V 0.05 / R 0.40

F · citation impact0.50 × 0.4 = 0.20
M · momentum0.50 × 0.15 = 0.07
V · venue signal0.50 × 0.05 = 0.03
R · text relevance †0.50 × 0.4 = 0.20

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