This paper investigates the role of thought leadership in enhancing managerial performance with a specific focus on the mediating role of social-skills and the moderating role of gender. This study employs a cross-sectional quantitative approach deploying a questionnaire to collect data from 523 line managers of registered SMEs in Ghana. The findings signal a significant and positive linkage between thought leadership and managerial performance mediated by social-skills. However, gender has no significant moderating effect on this relationship. The study emphasises the need for owner-managers to invest in the acquisition of thought leadership and social-skills to improve the performance and sustainability of their organisations. These results have important implications for managerial training and development in SMEs and provide a basis for future research in this area.